Why the study?
Does L-NAME infusion speed up phase II pulmonary Vo2 kinetics during heavy-intensity cycle exercise in men?
Population
7 men performing square-wave transitions from unloaded cycling to heavy-intensity exercise
Comparison
Intravenous infusion of L-NAME vs Control condition without prior intravenous…
Design
Other
Authors
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Informs Vo2 kinetics mechanisms; leaves open clinical translation or practice change.
Does L-NAME infusion speed up phase II pulmonary Vo2 kinetics during heavy-intensity cycle exercise in men?
Inhibition of nitric oxide synthase by L-NAME speeds up phase II pulmonary Vo2 kinetics during heavy-intensity exercise, suggesting that nitric oxide inhibits mitochondrial Vo2 at exercise onset.
Jones et al. (2004) studied this question.
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