Why the study?
Is the ACE I/D polymorphism associated with susceptibility to Alzheimer's disease in Slovak Caucasians?
Is the ACE I/D polymorphism associated with susceptibility to Alzheimer's disease in Slovak Caucasians?
The combination of ACE DD genotype and APOE*E4 allele significantly increases the risk of sporadic Alzheimer's disease in Slovak Caucasians.
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ACE DD plus APOE*E4 was associated with increased AD risk; leaves open value of genotyping for risk stratification or prevention.
Trebuňová et al. (2008) studied this question.
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