Why the study?
Is the ACE insertion/deletion polymorphism associated with the risk of Alzheimer's disease?
Is the ACE insertion/deletion polymorphism associated with the risk of Alzheimer's disease?
The ACE deletion homozygote genotype is associated with a reduced risk of Alzheimer's disease across diverse populations, likely due to linkage disequilibrium with the true risk factor.
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ACE D homozygosity associated with lower Alzheimer's risk; extends genetic evidence but leaves clinical utility open.
Lehmann et al. (2005) studied this question.
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