August 1, 1982CirculationOpen Access

Platelet release and thromboxane synthesis in symptomatic coronary artery disease.

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Why the study?

Does the measurement of plasma TXB2 and beta TG help detect or differentiate myocardial ischemia from infarction in patients admitted with chest pain?

Population

98 patients admitted to a coronary care unit with chest pain

Comparison

Serial measurement of plasma thromboxane B2 and… vs Patients with noncardiac chest pain

Design

Cohort

Authors

ABA C de BoerIJsselland Ziekenhuis ATA. G. G. TurpieMcMaster University RBR ButtShalamar Hospital

Discussion

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Implication

Plasma TXB2 and beta TG lack diagnostic utility in acute chest pain; hypothesis-generating for platelet activation biomarkers in ACS.

Structured PICO

Does the measurement of plasma TXB2 and beta TG help detect or differentiate myocardial ischemia from infarction in patients admitted with chest pain?

Population

98 patients admitted to a coronary care unit with chest pain (25 with myocardial infarction, 47 with angina, 26 with noncardiac chest pain)

Intervention

Serial measurement of plasma thromboxane B2 (TXB2) and beta thromboglobulin (beta TG) in plasma and urine

Comparator

Patients with noncardiac chest pain

Outcome

Plasma TXB2 and beta TG concentrationssurrogate

The measurement of beta TG and TXB2 lacks clinical value in detecting or differentiating myocardial ischemia from infarction in patients presenting with chest pain.

Cite This Study

Boer et al. (1982) studied this question.

synapsesocial.com/papers/6a763ef75db9de976abcb579 https://doi.org/10.1161/01.cir.66.2.327

View Full Paper

Ask AI

Bookmark

Platelet release and thromboxane synthesis in symptomatic coronary artery disease.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Platelet release and thromboxane synthesis in symptomatic coronary artery disease.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider