Why the study?
Does oral clonidine pretreatment reduce cardiovascular responses to stimuli during craniotomy in patients scheduled for supratentorial surgery?
Does oral clonidine pretreatment reduce cardiovascular responses to stimuli during craniotomy in patients scheduled for supratentorial surgery?
Oral clonidine pretreatment effectively attenuates hypertensive and tachycardic responses to noxious stimuli during craniotomy compared to diazepam.
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Supports clonidine over diazepam to blunt hemodynamic surges in supratentorial craniotomy; extends alpha-2 agonist premedication evidence and invites outcome trials.
Chadha et al. (1992) studied this question.
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