Why the study?
Does adenosine-induced controlled hypotension alter myocardial performance, blood flow, and metabolism in a canine open-chest model?
Does adenosine-induced controlled hypotension alter myocardial performance, blood flow, and metabolism in a canine open-chest model?
Adenosine-induced controlled hypotension in a canine model reduces myocardial work and oxygen uptake while increasing total myocardial blood flow without causing regional ischaemia.
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Should not change clinical hypotension practice; leaves open human translation of adenosine myocardial effects.
Öwall et al. (1986) studied this question.
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