Why the study?
Does moxonidine 0.2 mg b.i.d. reduce 24-h ambulatory blood pressure comparably to captopril 25 mg b.i.d. in patients with mild-to-moderate hypertension?
Population
26 patients with mild-to-moderate hypertension, 80.8% of whom had a history of concomitant diseases.
Comparison
Moxonidine 0.2 mg b.i.d. for 4 weeks. vs Captopril 25 mg b.i.d. for 4 weeks.
Design
RCT, parallel-group, double-blind
Follow-up
4 weeks
Authors
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Supports moxonidine as alternative to captopril for 24-h BP control; confirms comparable efficacy in mild-to-moderate hypertension.
Does moxonidine 0.2 mg b.i.d. reduce 24-h ambulatory blood pressure comparably to captopril 25 mg b.i.d. in patients with mild-to-moderate hypertension?
Moxonidine and captopril demonstrate comparable efficacy in lowering 24-hour ambulatory blood pressure in patients with mild-to-moderate hypertension.
Kraft et al. (1994) studied this question.
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