Key result
Left atrial appendage occlusion was associated with severe persistent peri-device flow in 4.5% of patients at 45 days, which could be effectively treated with percutaneous closure.
Why the study?
Severe peri-device leaks after LAA occlusion require lifelong oral anticoagulation in patients largely unsuitable for it, but data on leak incidence, characteristics, and management are scarce.
What is the incidence, characteristics, and management outcome of persistent peri-device flow after percutaneous left atrial appendage occlusion?
Cohort (n=200)
What is the incidence, characteristics, and management outcome of persistent peri-device flow after percutaneous left atrial appendage occlusion?
Severe peri-device leak occurs in approximately 4.5% of patients after LAA occlusion, is driven by larger LAA diameter and suboptimal deployment, and can be safely and effectively treated with percutaneous plug closure.
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Management of peri-device leaks after LAA occlusion in anticoagulation-ineligible patients requires further study; leaves open optimal strategies pending higher-level evidence.
Alkhouli et al. (2019) conducted a cohort in Left atrial appendage occlusion (n=200). Left atrial appendage occlusion was evaluated on Severe persistent peri-device flow. Left atrial appendage occlusion was associated with severe persistent peri-device flow in 4.5% of patients at 45 days, which could be effectively treated with percutaneous closure.
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