Key result
Vaccine or vaccine-reassortant rotavirus strains were detected in 4.7% (5 of 106) of immunocompetent children treated for rotavirus gastroenteritis.
Observational (n=106)
No
Vaccine and vaccine-reassortant rotavirus strains can be detected in a small percentage of children treated for gastroenteritis, though their exact pathogenic role remains unclear.
Findings do not alter rotavirus vaccination practices; leaves open vaccine strain pathogenicity in immunocompetent children.
Vaccine or vaccine-reassortant rotavirus strains were detected in fecal specimens from 5 of 106 (4.7%) immunocompetent children who required treatment for rotavirus gastroenteritis at a large pediatric hospital in Texas in 2009-2010. Four strains were related to pentavalent rotavirus vaccine, whereas one was related to monovalent rotavirus vaccine. The contribution of these strains to each patient's illness was unclear given that 2 patients had prominent respiratory symptoms and 2 were concurrently infected with another pathogen (group F adenovirus and norovirus). Continued monitoring is necessary to assess the role of vaccine strains and vaccine-reassortant strains in pediatric rotavirus infections.
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Boom et al. (2012) conducted an observational in rotavirus gastroenteritis (n=106). Vaccine or vaccine-reassortant rotavirus strains was evaluated on Detection of vaccine or vaccine-reassortant rotavirus strains in fecal specimens. Vaccine or vaccine-reassortant rotavirus strains were detected in 4.7% (5 of 106) of immunocompetent children treated for rotavirus gastroenteritis.
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