Population
Intact swine carotid artery
Design
Preclinical
Authors
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Links MAP kinase to contractile regulation in arteries; hypothesis-generating and requires human validation before any clinical consideration.
MAP kinase is activated during contractile stimulation in swine carotid arteries, suggesting it phosphorylates caldesmon to regulate smooth muscle contraction.
Katoch et al. (1995) studied this question.
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