Key result
Genetic factors substantially influence arterial stiffness in youth and young adults, with heritability estimates of 0.43 (95% CI 0.30-0.54) for radial PWV and 0.53 (95% CI 0.42-0.62) for foot PWV.
Observational (n=702)
Effect estimate: Heritability 0.43 (95% CI 0.30-0.54)
Arterial stiffness is substantially heritable in youth and young adults, with a significant portion of the genetic variance shared with diastolic blood pressure.
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Supports genetic research on early vascular phenotypes; leaves open clinical translation or interventions in youth.
Ge et al. (2007) conducted an observational in Arterial stiffness (n=702). Genetic factors was evaluated on Heritability of aorto-radial (radial) pulse-wave velocity (Heritability 0.43, 95% CI 0.30-0.54). Genetic factors substantially influence arterial stiffness in youth and young adults, with heritability estimates of 0.43 (95% CI 0.30-0.54) for radial PWV and 0.53 (95% CI 0.42-0.62) for foot PWV.
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