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May 1, 1982Journal of Biological ChemistryOpen Access

Na+-Ca2+ exchange in inside-out cardiac sarcolemmal vesicles.

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Authors

KPKenneth D. PhilipsonElectrophysiologyANA Y NishimotoAmerican Heart Association

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Overview

Investigates Na+-Ca2+ exchange in cardiac vesicles, suggesting implications for heart function.

Key Points

  • To explore the mechanisms of Na+-Ca2+ exchange in cardiac sarcolemmal vesicles.
  • Utilized inside-out cardiac sarcolemmal vesicles for experimentation.
  • Employed EGTA for calcium chelation during the analysis.
  • Identified the role of Na+-Ca2+ exchange in cardiac cellular processes.

Cite This Study

Philipson et al. (1982) studied this question.

synapsesocial.com/papers/6a778d11d8eb58afc2bdf2cfhttps://doi.org/10.1016/s0021-9258(18)34642-8
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Na+-Ca2+ exchange is affected by membrane potential in cardiac sarcolemmal vesicles.1980 · 113 citations
  2. 2Efflux of Ca2+ from cardiac sarcolemmal vesicles. Influence of external Ca2+ and Na+.1981 · 62 citations
  3. 3Effects of pH on Na+-Ca2+ exchange in canine cardiac sarcolemmal vesicles.1982 · 246 citations
  4. 4The Ca2+-pumping ATPase of heart sarcolemma. Characterization, calmodulin dependence, and partial purification.1981 · 475 citations
  5. 5The dependence of calcium efflux from cardiac muscle on temperature and external ion composition1968 · 1,025 citations