Why the study?
Blood pressure abnormalities may play an important role in macrovascular damage in type 1 diabetes, but little is known about these abnormalities and macrovascular damage in children with the disease.
Are ambulatory blood pressure abnormalities more prevalent in children with type 1 diabetes and associated with increased carotid intima media thickness compared to controls?
Population
57 children with type 1 diabetes and 29 control children without diabetes
Comparison
Children with type 1 diabetes vs control children without diabetes
Design
Observational cross-sectional study
Authors
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ABPM abnormalities may signal early macrovascular risk in pediatric T1D; leaves open need for prospective trials before clinical adoption.
Are ambulatory blood pressure abnormalities more prevalent in children with type 1 diabetes and associated with increased carotid intima media thickness compared to controls?
Children with type 1 diabetes have a significantly higher prevalence of ambulatory blood pressure abnormalities, which interact with BMI to increase carotid intima media thickness, an early marker of atherosclerosis.
Glackin et al. (2019) studied this question.