Population
250 stable heart failure patients with trimonthly blood sampling
Comparison
17 repeatedly measured cytokines and cytokine receptors
Design
Prospective cohort study
Follow-up
Median 2.2 (25th-75th percentile, 1.4-2.5) years
Authors
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May aid HF risk stratification; hypothesis-generating and requires validation before clinical adoption.
Temporal patterns of serially measured cytokines and cytokine receptors, particularly TNFSF13B and IL1R1, may contribute to personalized risk assessment in stable heart failure.
Bouwens et al. (2020) studied this question.
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