Why the study?
Are plasma Endothelin-1 (ET-1) and neuropeptide Y concentrations elevated in patients with mild-to-moderate essential hypertension compared to healthy volunteers?
Are plasma Endothelin-1 (ET-1) and neuropeptide Y concentrations elevated in patients with mild-to-moderate essential hypertension compared to healthy volunteers?
Elevated plasma ET-1 and neuropeptide Y levels in patients with mild-to-moderate essential hypertension suggest a role for ET-1 in the development and maintenance of elevated blood pressure.
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Elevated ET-1 and neuropeptide Y levels may support a pathogenic role in hypertension; hypothesis-generating and should not yet change practice.
Januszewicz et al. (1994) studied this question.
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