Why the study?
Does dobutamine improve mechanical efficiency and energy transfer in stunned porcine myocardium?
Population
10 open chest anaesthetised pigs with stunned myocardium induced by two sequences of 10 min occlusion and 30…
Comparison
Atrial pacing and additional infusion of 2… vs Baseline and stunning conditions prior to…
Design
Preclinical
Authors
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Suggests dobutamine improves efficiency in stunned myocardium; leaves open translation to clinical post-ischemic stunning.
Does dobutamine improve mechanical efficiency and energy transfer in stunned porcine myocardium?
In stunned porcine myocardium, dobutamine restores the efficiency of energy transfer without causing an excessive increase in myocardial oxygen consumption.
Krams et al. (1993) studied this question.
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