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October 16, 2013Diabetes CareOpen Access

ICH was significantly associated with decreased prevalence (OR 0.70; 95% CI 0.62-0.80) and progression (OR 0.77; 95% CI 0.66-0.90) of coronary artery calcification.

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Why the study?

Does ideal cardiovascular health reduce the prevalence and progression of coronary artery calcification in adults with and without type 1 diabetes?

Population

1,177 adults from the prospective Coronary Artery Calcification in Type 1 Diabetes study

Design

Cohort

Authors

AAAmy C. AlmanDMDavid M. MaahsMRMarian Rewers

Discussion

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Overview

Supports ideal cardiovascular health promotion in diabetes; extends observational CAC data but remains hypothesis-generating.

Structured PICO

Does ideal cardiovascular health reduce the prevalence and progression of coronary artery calcification in adults with and without type 1 diabetes?

P
Population
1,177 adults (546 with type 1 diabetes and 631 without diabetes) from the prospective Coronary Artery Calcification in Type 1 Diabetes study
I
Intervention
Ideal cardiovascular health (ICH) metrics (smoking, BMI, physical activity, diet, total cholesterol, blood pressure, and fasting plasma glucose)
O
Outcome
Prevalence and progression of coronary artery calcification (CAC)surrogate

Ideal cardiovascular health metrics are rarely met but are significantly associated with reduced prevalence and progression of coronary artery calcification in adults with and without type 1 diabetes.

Cite This Study

Alman et al. (2013) studied this question.

synapsesocial.com/papers/6a7955258d250a4360f37ebahttps://doi.org/10.2337/dc13-0997
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Progression of Coronary Artery Calcification in Type 1 Diabetes2003 · 140 citations
  2. 2Burden and progression of arterial calcification in type 1 diabetes predicts future cardiovascular disease2025 · 1 citations
  3. 3Cardiovascular health in adolescents with type 1 diabetes: The SEARCH CVD Study2014 · 53 citations
  4. 4Prospective Association Between Inflammatory Markers and Progression of Coronary Artery Calcification in Adults With and Without Type 1 Diabetes2013 · 30 citations
  5. 5Association of a Favorable Cardiovascular Health Profile With the Presence of Coronary Artery Calcification2015 · 55 citations