Population
St. Jude bileaflet valve prosthesis (in vitro model)
Design
Preclinical
Authors
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May signal thrombosis risk with bileaflet valves; leaves open clinical relevance pending in vivo studies.
In vitro testing of the St. Jude bileaflet valve reveals elevated turbulent shear stresses and flow separation that could theoretically predispose to blood element damage and thrombosis.
Woo et al. (1986) studied this question.
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