March 13, 1995FEBS LettersOpen Access

Molecular cloning and functional expression of a novel potassium channel β‐subunit from human atrium

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Population

Xenopus oocytes expressing cloned hKv beta 3 from human atrium

Design

Preclinical

Authors

KMKumud MajumderCity College of New York MBMariella De BiasiCalifornia University of Pennsylvania ZWZhiguo WangON Semiconductor (United States)

Discussion

Member takes

Implication

hKvβ3 may diversify human atrial K+ currents; leaves open its role in repolarization or arrhythmias.

Structured PICO

Population

Xenopus oocytes expressing cloned hKv beta 3 from human atrium

Intervention

Co-expression of hKv beta 3 with hKv1.4, hKv1.5, hKv1.1, hKv1.2, or hKv2.1 channels

Outcome

Inactivation kinetics of K+ currentssurrogate

The cloning of hKv beta 3 reveals a novel human atrial potassium channel subunit that specifically modulates the inactivation kinetics of a subset of Kv1 channels.

Cite This Study

Majumder et al. (1995) studied this question.

synapsesocial.com/papers/6a7973b8fb5b6b43000db3ea https://doi.org/10.1016/0014-5793(95)00120-x

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Molecular cloning and functional expression of a novel potassium channel β‐subunit from human atrium

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Molecular cloning and functional expression of a novel potassium channel β‐subunit from human atrium

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider