Key result
High concentrations of ApoCI and ApoCIII were associated with 49% higher triglyceride concentrations and 26% lower visceral fat area compared to low concentrations (both P < 0.001).
Why the study?
Are high concentrations of ApoCI and ApoCIII associated with increased triglycerides and decreased fat mass in men with the metabolic syndrome?
Population
98 men with the metabolic syndrome
Comparison
High concentrations of plasma apolipoprotein CI… vs Low concentrations of plasma ApoCI and ApoCIII
Design
Cross-sectional
Authors
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Should not yet change practice; extends mouse ApoC findings to human metabolic syndrome but remains hypothesis-generating.
Cross-Sectional (n=98)
Are high concentrations of ApoCI and ApoCIII associated with increased triglycerides and decreased fat mass in men with the metabolic syndrome?
p-value: p=< 0.001
High concentrations of ApoCI and ApoCIII are associated with increased triglycerides and decreased visceral fat mass in men with metabolic syndrome, translating previous mouse model findings into human pathophysiology.
Ham et al. (2008) conducted a cross-sectional in Metabolic syndrome (n=98). High concentrations of ApoCI and ApoCIII vs. Low concentrations of ApoCI and ApoCIII was evaluated on Triglyceride concentrations and visceral fat area (p=< 0.001). High concentrations of ApoCI and ApoCIII were associated with 49% higher triglyceride concentrations and 26% lower visceral fat area compared to low concentrations (both P < 0.001).
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