Why the study?
Chronic diseases and depression both increase the risk of functional impairment, but previous research evidence has been controversial.
Is comorbid depression associated with functional impairment in middle-aged and elderly Chinese adults with vascular disease or diabetes mellitus?
Population
Middle-aged and elderly Chinese people with vascular disease or diabetes mellitus
Comparison
Comorbid depression vs no depression across vascular disease and diabetes mellitus
Design
Cross-sectional study
Key result
Comorbid depression in middle-aged and elderly Chinese adults with vascular disease or diabetes was significantly associated with lower functional status (ADL/IADL adjusted ORs 3.60-7.72, p<0.001).
Authors
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Depression may flag functional impairment risk among vascular disease or diabetes patients; leaves open causality and intervention effects in cross-sectional data.
Cross-Sectional
Is comorbid depression associated with functional impairment in middle-aged and elderly Chinese adults with vascular disease or diabetes mellitus?
Effect estimate: OR 3.60-7.72
p-value: p=<0.001
Comorbid depression significantly increases the odds of functional impairment in middle-aged and elderly adults with vascular disease or diabetes, highlighting the need for concurrent depression management.
Zhao et al. (2023) conducted a cross-sectional in Vascular disease and diabetes mellitus. Comorbid depression was evaluated on Lower functional status (Activity of Daily Living/Instrumental Activity of Daily Living) (OR 3.60-7.72, p=<0.001). Comorbid depression in middle-aged and elderly Chinese adults with vascular disease or diabetes was significantly associated with lower functional status (ADL/IADL adjusted ORs 3.60-7.72, p<0.001).
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