Why the study?
Does sequential incremental intravenous infusions of sodium nitroprusside reduce mean arterial pressure in male patients with essential hypertension?
Does sequential incremental intravenous infusions of sodium nitroprusside reduce mean arterial pressure in male patients with essential hypertension?
The magnitude of the vasodepressor response to sodium nitroprusside in hypertensive patients is determined by predrug blood pressure and the degree of sympathetic response.
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Sympathetic tone may predict nitroprusside response variability in hypertension; leaves open validation in prospective trials.
Shepherd et al. (1983) studied this question.
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