January 1, 1997Thrombosis and Haemostasis

Activation of the Fibrinolytic System in Patients with Coronary Artery Disease and Hyperfibrinogenemia

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Population

224 consecutive patients undergoing elective coronary angiography, with a selected subgroup of 100 patients…

Design

Cross-sectional

Authors

DSDirk SteinFOM University of Applied Sciences for Economics and Management MHMichael HeinsLeibniz University Hannover FSF. C. SchoebelDüsseldorf University Hospital

Discussion

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Implication

Hyperfibrinogenemia links to fibrinolytic activation in CAD; hypothesis-generating and should not yet change practice.

Structured PICO

Population

224 consecutive patients undergoing elective coronary angiography, with a selected subgroup of 100 patients (81 men, 19 women) having fibrinogen either >= 3.5 g/l (n=70) or <= 2.5 g/l (n=30).

Outcome

Concentrations of plasmin-alpha 2-antiplasmin complex (PAP) and tissue plasminogen activator (t-PA) antigensurrogate

Elevated fibrinogen levels in patients with coronary artery disease are associated with an activation of the endogenous fibrinolytic system.

Cite This Study

Stein et al. (1997) studied this question.

synapsesocial.com/papers/6a7a981302ab7a73dd02fe87 https://doi.org/10.1055/s-0038-1656087

Topics

Hypertension management

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Activation of the Fibrinolytic System in Patients with Coronary Artery Disease and Hyperfibrinogenemia

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Activation of the Fibrinolytic System in Patients with Coronary Artery Disease and Hyperfibrinogenemia

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider