Why the study?
Does saralasin affect blood pressure control during general anesthesia?
Does saralasin affect blood pressure control during general anesthesia?
The use of saralasin allows for the investigation of the renin-angiotensin system's role in blood pressure regulation during general anesthesia.
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May aid research on renin-angiotensin effects during anesthesia; leaves open any clinical role.
Variation of plasma renin activity has been shown to occur during anesthesia, but its significance remains obscure. The recent development of a specific angiotensin II antagonist, saralasin, allows the delineation of the role of the renin-angiotensin system in blood pressure control during anesthesi
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Miller et al. (1978) studied this question.
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