Why the study?
Does drug treatment reducing blood pressure improve visceral changes in patients with severe hypertension?
Population
112 patients with severe hypertension treated in an outpatient clinic
Comparison
Drug treatment achieving reduction in mean blood… vs Patients with poorer regulation of blood pressure
Design
Cohort
Follow-up
average period of 3.5 years
Authors
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BP reduction to ≤133% normal was associated with end-organ regression in severe hypertension; leaves open optimal targets in contemporary cohorts.
Does drug treatment reducing blood pressure improve visceral changes in patients with severe hypertension?
Effective blood pressure reduction in severe hypertension significantly regresses cardiac and retinal end-organ damage and preserves renal function.
Dorph et al. (1970) studied this question.
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