Key result
Brown adipose tissue had an apparent prevalence of 8.5% and an estimated true prevalence of 64%, and its presence correlated negatively with age, body mass index, and fasting glucose.
Population
2,934 adult patients who underwent [18F]fluorodeoxyglucose PET-CT scans
Design
Cohort
Authors
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No change to clinical practice indicated; leaves open BAT's causal metabolic role for prospective trials.
Observational (n=2,934)
Brown adipose tissue is estimated to be present in the majority of adult humans, and its presence correlates negatively with BMI and fasting glucose, suggesting a role in energy homeostasis.
Lee et al. (2010) conducted an observational in Adults undergoing PET-CT (n=2,934). Presence of brown adipose tissue (BAT) vs. Absence of BAT was evaluated on Apparent prevalence of brown adipose tissue on initial scan. Brown adipose tissue had an apparent prevalence of 8.5% and an estimated true prevalence of 64%, and its presence correlated negatively with age, body mass index, and fasting glucose.