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January 1, 1991Biochemistry

Molecular cloning of rat cardiac troponin I and analysis of troponin I isoform expression in developing rat heart

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Authors

AMAnne M. MurphyPediatric / Congenital Cardiology LJLawrence JonesJohns Hopkins University HSHarold F. SimsCincinnati Children's Hospital Medical Center

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Implication

Sequence data for rat cardiac troponin I enables rodent models; leaves open isoform roles in human cardiac development.

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Murphy et al. (1991) studied this question.

synapsesocial.com/papers/6a7cb6896111ec194fa8af2b https://doi.org/10.1021/bi00217a018

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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Troponin I Switching in the Developing Heart1989 · 211 citations
2cDNA Clone and Expression Analysis of Rodent Fast and Slow Skeletal Muscle Troponin I mRNAs1989 · 80 citations
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4Differential effects of pH on calcium activation of myofilaments of adult and perinatal dog hearts. Evidence for developmental differences in thin filament regulation.1986 · 84 citations
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