Population
Chinese hamster ovary cells stably transfected with the complementary DNA of the alpha 1, beta and alpha…
Comparison
Co-expression of the alpha 1 subunit with the… vs Expression of the alpha 1 subunit alone, or…
Design
Preclinical
Authors
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Modulates L-type calcium channel properties in animal models; leaves open applicability to human cardiovascular disease.
The beta and alpha 2/delta subunits interact with the alpha 1 subunit of the L-type calcium channel to modulate its electrophysiological properties, including enhancing current density and altering kinetics.
Welling et al. (1993) studied this question.
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