Why the study?
Is the M235T polymorphism in the angiotensinogen gene associated with essential hypertension in Romanian patients?
Population
59 Romanian patients, comprising 38 with essential hypertension and 21 normotensive controls.
Comparison
Presence of M235T polymorphism in the… vs Normotensive controls
Design
Case-control
Authors
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Supports M235T association with hypertension in Romanians; hypothesis-generating and requires larger replication before clinical consideration.
Is the M235T polymorphism in the angiotensinogen gene associated with essential hypertension in Romanian patients?
The M235T polymorphism in the angiotensinogen gene appears to be associated with essential hypertension in a Romanian cohort.
Procopciuc et al. (2002) studied this question.
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