Population
Human kidney tissue homogenate, human chorion decidua tissue, and human plasma
Design
Preclinical
Authors
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Does not support clinical targeting of this protease; leaves open its physiologic role in human prorenin activation.
Identifies a candidate cysteine protease in the human kidney responsible for the authentic processing of prorenin into active renin.
Shinagawa et al. (1990) studied this question.
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