Population
Female Yucatan miniature swine
Comparison
Exercise training on a motor-driven treadmill… vs Cage confined (sedentary) for 13-20 weeks
Design
Preclinical
Follow-up
13-20 weeks
Authors
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No impact of exercise on endothelium-independent coronary vasodilation in swine; leaves open endothelial modulation or human translation.
In a swine model, exercise training for 13-20 weeks did not alter endothelium-independent vasodilation in proximal coronary arteries, while both groups showed potent vasodilation to bradykinin, substance P, and A-23187.
Oltman et al. (1995) studied this question.
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