Key result
Elevated microRNA-210-3p is linked to HFrEF versus HFpEF at a 5.03 cut-off.
Why the study?
Are microRNA-210-3p and other biomarkers (NT-proBNP, sST2, galectin-3) differentially expressed in HFrEF compared to HFpEF?
Cross-Sectional (n=270)
No
Are microRNA-210-3p and other biomarkers (NT-proBNP, sST2, galectin-3) differentially expressed in HFrEF compared to HFpEF?
MicroRNA-210-3p and other biomarkers are significantly elevated in HFrEF compared to HFpEF and correlate with the MAGGIC score, suggesting potential utility in a multi-marker diagnostic approach.
No takes yet. Share an insight, caveat, or question.
Beem et al. (2025) conducted a cross-sectional in Heart failure (n=270). HFrEF vs. HFpEF was evaluated on Expression levels of microRNA-210-3p, NT-proBNP, sST2, and galectin-3. Biomarkers including microRNA-210-3p were significantly higher in patients with HFrEF compared to those with HFpEF, with a microRNA-210-3p cut-off of 5.03.
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