Population
4 to 5 day old infant mice, untreated adult mice, and adult mice treated with cortisone
Comparison
Infection with Conn.-5 strain of Coxsackie… vs Untreated adult mice and infant mice
Design
Preclinical
Follow-up
7 days
Authors
Loading...
May promote cortisone-enhanced cardiac and hepatic injury in adult Coxsackie infection; leaves open relevance to human viral myocarditis.
Cortisone administration alters host-virus interactions in adult mice, expanding Coxsackie virus multiplication and tissue injury to organs like the heart and liver.
Boring et al. (1955) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: