Why the study?
Does sublingual nifedipine acutely improve aortic impedance, compliance, and resistance in patients with hypertension?
Population
16 ethnic Chinese patients, age matched. Excluded: clinical evidence of heart failure, valvular or…
Comparison
Sublingual nifedipine 10 mg vs Baseline measurements before nifedipine…
Design
Other
Follow-up
10-30 minutes
Authors
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Nifedipine acutely lowers pressure and resistance without reducing proximal aortic stiffness; hypothesis-generating for differential vascular effects, needs prospective confirmation.
Does sublingual nifedipine acutely improve aortic impedance, compliance, and resistance in patients with hypertension?
Sublingual nifedipine acutely reduces peripheral arteriolar tone and arterial pressure in hypertensives, but does not improve the stiffness of the proximal aorta.
Chang et al. (1990) studied this question.
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