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March 30, 1996BMJOpen Access

Low blood pressure and dementia in elderly people: the Kungsholmen project

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Why the study?

Is low blood pressure associated with an increased prevalence of dementia in elderly people?

Population

1642 subjects aged 75-101 years from the Kungsholmen district of Stockholm, Sweden.

Comparison

Systolic blood pressure <=140 mm Hg or diastolic… vs Systolic blood pressure >140 mm Hg or diastolic…

Design

Cross-sectional

Authors

MVMatti ViitanenKarolinska University Hospital
Laura Fratiglioni
Laura FratiglioniCross-Cutting Cardiology
Bengt Winblad
Bengt WinbladLinköping University

Discussion

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Implication

Low systolic BP was associated with higher dementia prevalence; hypothesis-generating and should not change practice pending longitudinal data.

Structured PICO

Is low blood pressure associated with an increased prevalence of dementia in elderly people?

P
Population
1642 subjects aged 75-101 years from the Kungsholmen district of Stockholm, Sweden.
I
Intervention
Systolic blood pressure <=140 mm Hg or diastolic blood pressure <=75 mm Hg
C
Comparator
Systolic blood pressure >140 mm Hg or diastolic blood pressure >75 mm Hg
O
Outcome
Prevalence and adjusted odds ratio of dementiahard clinical

Relatively low blood pressure is inversely related to the prevalence of dementia in elderly people, which may be a complication of the dementia process.

Cite This Study

Viitanen et al. (1996) studied this question.

synapsesocial.com/papers/6a7d4656b97b7d2d4f83e279https://doi.org/10.1136/bmj.312.7034.805
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Senile Dementia of the Binswanger Type1987 · 372 citations
  2. 2Clinical Diagnosis of Alzheimer's Disease and Other Dementias in a Population Survey1992 · 148 citations
  3. 3Low blood pressure and blood glucose levels in Alzheimer's disease Evidence for a hypometabolic disorder?1993 · 114 citations
  4. 4Changes in Blood Glucose and Insulin Secretion in Patients with Senile Dementia of Alzheimer Type1983 · 142 citations
  5. 5Cerebral Blood Flow and Metabolism Studies in Multi-Infarct Dementia1991 · 21 citations