Population
Spontaneously hypertensive rat and Dahl salt-sensitive rat models, as well as recombinant inbred strains…
Design
Preclinical
Authors
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Scnn1b remains a positional candidate in rat hypertension models; leaves open noncoding variants or linked genes as drivers of the chromosome 1 QTL.
While the Scnn1b gene maps to a blood pressure-associated region on rat chromosome 1, it lacks coding sequence mutations in SHR and Dahl salt-sensitive rat models of hypertension.
Huang et al. (1995) studied this question.
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