Population
Freshly isolated rat juxtaglomerular cells (JGC) (n = 9 preparations / 18 superfusion chambers)
Comparison
Adenosine deaminase type II, purified ADA type… vs Control superfusion medium
Design
Preclinical
Follow-up
100 min
Authors
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Supports isolated rat JG cell model for renin studies; leaves open clinical relevance of ADA effects on RSR.
Superfusion of isolated rat juxtaglomerular cells is a viable model for studying renin secretion at the cellular level, demonstrating stimulatory effects of ADA and albumin.
Albinus et al. (1998) studied this question.
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