Key result
Low-molecular-weight dextran did not reduce mortality in acute myocardial infarction compared to control and increased congestive heart failure.
RCT (n=102)
Open-label
Randomized according to a preconceived list, stratified by sex and recognized previous infarction
No
Answers are grounded in this paper and cite their sources.
monary congestion, the decision being left to the attending physician.Myocardial infarction was defined according to the standard rules of this department (Enger et al., 1963), requiring typical E.C.G. pattern with Q waves or ST changes.When the E.C.G. pattern was not obvious the diagnosis wAs made if three of the following criteria were present: a rise in the sedimentation rate, serum glutamic oxaloacetic transaminase (G.O.T.) valies above 40 units, a typical temperature curve, and a lucocyte count above 9,000.The patients admitted to the study were randomized into two groups according to a preconceived list.Separate criteria were made for the two sexes and for the patients with recog- nized previous infarction.
No takes yet. Share an insight, caveat, or question.
Borchgrevink et al. (1966) conducted an RCT in Acute myocardial infarction (n=102). Low-molecular-weight dextran (Rheomacrodex) 10% in glucose vs. Routine treatment alone (including anticoagulant therapy) was evaluated on In-hospital mortality. Low-molecular-weight dextran did not reduce mortality in acute myocardial infarction compared to control and increased congestive heart failure.
Synapse has enriched 10 related papers. Consider them for comparative context: