Population
Endothelial cells (EC) cultured from bovine aortae and luminally perfused rabbit aortae
Design
Preclinical
Authors
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Agonist-specific endothelial release patterns may enable selective targeting; leaves open translation to human vascular function or therapy.
Different agonists induce distinct temporal patterns of EDRF and PGI2 release in endothelial cells, indicating that their release mechanisms or time courses are not necessarily coupled.
Mitchell et al. (1992) studied this question.
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