Why the study?
Do offspring of malignant hypertensive parents exhibit early hemodynamic and metabolic abnormalities compared to offspring of normotensive parents?
Population
77 subjects with blood pressure <140/90 mm Hg, comprising 42 offspring of malignant hypertensive parents and…
Comparison
Offspring of malignant hypertensive parents (OMH) vs Offspring of normotensive parents (ONT)
Design
Cross-sectional
Authors
Loading...
Associates parental malignant hypertension with early abnormalities in normotensive offspring; hypothesis-generating for future risk, requiring longitudinal confirmation.
Do offspring of malignant hypertensive parents exhibit early hemodynamic and metabolic abnormalities compared to offspring of normotensive parents?
Offspring of malignant hypertensive parents demonstrate early hemodynamic, neurohumoral, and metabolic alterations typical of hypertensive metabolic syndrome even while normotensive.
Lopes et al. (2001) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: