Why the study?
Does nonpulsatile left ventricular bypass cause adverse hemodynamic or metabolic effects compared to pulsatile bypass in unanesthetized calves?
Population
16 alert, active calves (n=9 for nonpulsatile bypass, n=7 for pulsatile bypass)
Comparison
Nonpulsatile left ventricular bypass using a… vs Prebypass control values and pulsatile bypass…
Design
Preclinical
Follow-up
up to 35 days
Authors
Loading...
No practice change from this calf model; hypothesis-generating for nonpulsatile LVAD effects in humans.
Does nonpulsatile left ventricular bypass cause adverse hemodynamic or metabolic effects compared to pulsatile bypass in unanesthetized calves?
Prolonged nonpulsatile left ventricular bypass in unanesthetized calves is feasible and does not cause adverse metabolic or renal effects.
G. Gilbert Johnston (1976) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: