Why the study?
What is the incidence and what are the risk factors for neuroleptic malignant syndrome in patients receiving antipsychotic treatment?
Population
n=564 patients admitted to the Department of Psychiatry of the Hospital of Oita Medical University receiving…
Design
Cohort
Authors
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May warrant vigilance for neuroleptic malignant syndrome in agitated or malnourished patients on high-dose haloperidol; hypothesis-generating from observational data and requires prospective validation.
What is the incidence and what are the risk factors for neuroleptic malignant syndrome in patients receiving antipsychotic treatment?
The incidence of neuroleptic malignant syndrome in this Japanese psychiatric cohort was 1.8%, with high-dose haloperidol and specific clinical signs identified as risk factors.
Naganuma et al. (1994) studied this question.
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