Differences in pH Management and Pulsatile/Nonpulsatile Perfusion During Cardiopulmonary Bypass Do Not Influence Renal Function

100 patients with normal preoperative renal function undergoing elective coronary artery bypass surgery

Pulsatile perfusion (pulse pressure 18.0 +/- 1.5 mm Hg) or nonpulsatile perfusion (mean pulse pressure 1.9 +/- 0.4 mm Hg) combined with alpha-stat (mean PaCO2 41.2 +/- 0.9 mm Hg) or pH-stat (mean PaCO2 60.6 +/- 1.7 mm Hg) pH management during hypothermic cardiopulmonary bypass

Compared against each other across four different cardiopulmonary bypass management groups

Perioperative renal function (mean urine output, fractional excretion of sodium and potassium, renal failure index, postoperative creatinine, and blood urea nitrogen)surrogate