Key points are not available for this paper at this time.
Design
Review
This review summarizes the structure and multifunctional roles of CARP in cardiac development, sarcomere integrity, and various cardiovascular and muscle diseases, highlighting its potential as a diagnostic marker and therapeutic target.
Cardiac ankyrin repeat protein (CARP) not only serves as an important component of muscle sarcomere in the cytoplasm, but also acts as a transcription co-factor in the nucleus. Previous studies have demonstrated that CARP is up-regulated in some cardiovascular disorders and muscle diseases; however, its role in these diseases remains controversial now. In this review, we will discuss the continued progress in the research related to CARP, including its discovery, structure, and the role it plays in cardiac development and heart diseases.
No takes yet. Share an insight, caveat, or question.
Na Zhang (2016) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: