Why the study?
Does simultaneous enalapril administration prevent doxorubicin-induced cardiomyopathy and improve survival in a canine model?
Does simultaneous enalapril administration prevent doxorubicin-induced cardiomyopathy and improve survival in a canine model?
Simultaneous treatment with enalapril improves survival and attenuates ventricular dysfunction in a canine model of doxorubicin-induced cardiomyopathy.
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Does not support enalapril co-administration with doxorubicin in patients; leaves open translation of canine benefits to clinical practice.
Vaynblat et al. (2002) studied this question.
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