This case highlights a rare presentation of coumarin-induced necrosis involving the penis and feet in a patient treated for pulmonary embolism.
Alerts clinicians to atypical penile sites in coumarin necrosis; extends the phenotypic spectrum but remains hypothesis-generating.
A 57-year-old male patient with advanced adenocarcinoma of the lung, who was administered oral anticoagulant therapy because of pulmonary embolism, developed coumarin necrosis confined to the penis and feet. To our knowledge, this patient showing acral involvement is the seventh case of coumarin-induced penile necrosis reported to date.
No takes yet. Share an insight, caveat, or question.
Harmanyeri et al. (1998) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: