Population
frog ventricle preparations
Comparison
electrical stimulation, acetylcholine, and… vs quiescent preparations or baseline conditions
Design
Preclinical
Authors
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Does not inform clinical practice; hypothesis-generating for differential Ca handling in cardiac muscle, requiring mammalian validation.
Both acetylcholine and epinephrine increase calcium permeability in frog ventricular muscle, but epinephrine causes a rapid drop in tension, suggesting increased intracellular calcium storage.
Delahayes et al. (1972) studied this question.
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