Population
Depolarized smooth muscle from toad stomach
Comparison
Acetylcholine (ACh) stimulation vs Unstimulated muscle
Design
Preclinical
Authors
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ACh alters Ca flux in depleted smooth muscle; hypothesis-generating for autonomic regulation, requires mammalian validation before any clinical inference.
Acetylcholine stimulation increases both calcium uptake and efflux in depolarized toad stomach smooth muscle, particularly in calcium-depleted states.
Potter et al. (1970) studied this question.
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