Population
Poliovirus-infected HeLa cells and uninfected control cells
Comparison
Poliovirus infection vs Uninfected control HeLa cells
Design
Preclinical
Follow-up
intervals after infection
Authors
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May link monovalent cation shifts to poliovirus cytotoxicity; hypothesis-generating for tonicity-targeted interventions.
Poliovirus infection in HeLa cells induces significant alterations in monovalent cation metabolism and cell volume, suggesting tonicity changes may contribute to viral cytotoxicity.
C. N. Nair (1981) studied this question.
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