Why the study?
Do adiponectin gene variants influence insulin resistance, type 2 diabetes, and cardiovascular disease risk?
Population
Populations from published studies assessing the genetic influences of adiponectin locus variants
Comparison
Adiponectin locus variants vs Carriers of other genotypes
Design
Meta-analysis
Authors
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Supports adiponectin variant testing for refined T2D risk stratification; extends meta-analytic confirmation of locus effects on insulin resistance and CVD.
Do adiponectin gene variants influence insulin resistance, type 2 diabetes, and cardiovascular disease risk?
Polymorphisms at the adiponectin locus are significant predictors of circulating adiponectin levels, insulin sensitivity, and atherosclerosis risk.
Menzaghi et al. (2007) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: